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The underlying cause of VPD remains not well understood. No adjuvant treatment was used in our case because of the favorable issue of the disease. Complete resolution of Paget disease of the vulva with imiquimod cream. However, the results are not encouraging as the recurrence rates are high. Recurrence rates in invasive VPD are high: Long-term monitoring of patients is recommended, and repeat surgical excision is often necessary [ 24 ]. Many years after the diagnosis of PDV, patients may be diagnosed with cancer of the bladder.

Advanced Cancer and Caregivers. After finishing her training as a gynaecologist in , she followed a fellowship in gynaecologic oncology at the Department of Gynaecologic Oncology of the Leiden University Medical Center, the Netherlands Prof. Am I Having a Heart Attack? The exact cause of Paget's disease is unknown. Recurrence rates in invasive VPD are high: Organizations Supporting this Disease.

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Paget’s Disease of the Vulva

    What is the prognosis for people with Paget disease of the breast? Migraine Triggers You Can Avoid. New study may lead to improved treatment for type 2 diabetes. See answer Have a question? A positive test result for EMPD shows increased numbers of large polygonal cells with a pale bluish cytoplasm, large nucleus and nucleolus, infiltrating the epidermal layer. A scalpel is used to remove a small wedge of tissue. The prognosis, or outlook, for people with Paget disease of the breast depends on a variety of factors, including the following: Symptoms include long-standing tenderness and itching, irritation, and burning sensation. The most common bones affected by Paget's disease include the spine, the thigh bone femur , the pelvis, the skull, the collarbone clavicle , and the upper arm bone humerus.

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